Anna L Gloyn, PhD, Professor, Department of Pediatrics & Genetics, Stanford University

Research Description: The overarching goal of Dr Gloyn’s research is to identify molecular and cellular mechanisms underlying defects in energy balance and metabolism that contribute to diabetes and obesity. The consistent focus of her lab has been to capitalize on naturally occurring genetic variation which alters risk for diabetes and related metabolic traits as a tool to identify critical genes and pathways in humans. Her research integrates genetic discovery efforts with functional genomics and mechanistic studies in authentic human cell models and model organisms. Projects range from detailed mechanistic studies at individual disease-associated loci to genome-wide efforts to perturb gene function at scale using state-of-the-art genomeediting approaches. Dr Gloyn plays a leading role in large international consortia for genetic discovery including the NIDDK Accelerated Medicines Partnership for Common Metabolic Disease (AMP-CMD) and the International Common Disease Alliance where she co-leads the working group for Diabetes and Metabolic Disease. Locally, Dr Gloyn is Co-Director of the Stanford Diabetes Research Center (SDRC) Pilot & Feasibility program and the SDRC Enrichment program. Dr. Gloyn collaborates extensively with many members of the NORC.